Influence of dietary iodine deficiency on the thyroid gland in Slc26a4-null mutant mice
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چکیده
منابع مشابه
Influence of dietary iodine deficiency on the thyroid gland in Slc26a4-null mutant mice
BACKGROUND Pendred syndrome (PDS) is an autosomal recessive disorder characterized by sensorineural hearing impairment and variable degree of goitrous enlargement of the thyroid gland with a partial defect in iodine organification. The thyroid function phenotype can range from normal function to overt hypothyroidism. It is caused by loss-of-function mutations in the SLC26A4 (PDS) gene. The seve...
متن کاملthe influence of the neo-platonic concept of poetic imagination on wordsworth’s poetry
بر اساس نظریه افلاطون در باره شعر خلاقیت هنری مورد انتقاد قرار گرفته است. نظریه کلی در مورد شعر این بود که شعر از ظواهرتقلید میکند و نه حقیقت. چون سایه ای از حقیقت است. اما با پیدایش فلسفه نو افلاطونی، انتقاتات قبلی در مورد شعر و شاعری اصلاح شد. فلوطین در کتاب انئید، اساس خلق هنری را بر محور مُثل افلاطونی قرار داد. وی باور داشت که هنر مندان در خلق آثار هنری، تحت تاثیر مُثل افلاطونی بوده و عوالمی ...
The Influence of Pregnancy and Castration on the Iodine and Phosphorus Metabolism of the Thyroid Gland
It has been demonstrated by the investigations of Seidell and Fengerl that there exists a distinct seasonal variation in the iodine content of the thyroid gland from domestic animals. For the purpose of establishing more definite conclusions regarding the probable influence of pregnancy and oi castration upon the thyroid activity, the present investigation was conducted on composite lots of gla...
متن کاملThe Influence of Pregnancy and Castration on the Iodine and Phosphorus Metabolism of the Thyroid Gland
It has been demonstrated by the investigations of Seidell and Fengerl that there exists a distinct seasonal variation in the iodine content of the thyroid gland from domestic animals. For the purpose of establishing more definite conclusions regarding the probable influence of pregnancy and oi castration upon the thyroid activity, the present investigation was conducted on composite lots of gla...
متن کاملIodine Metabolism of the Thyroid Gland*
Because of the similarity in structure between diiodotyrosine and thyroxine, Harington and Barger (1) suggested that the former is the precursor of thyroxine in the thyroid gland. The formation of thyroxine from diiodotyrosine has been demonstrated lately in vitro (2, 3). Recent data (4, 5) obtained with radioiodine used without carrier indicate the rates of incorporation of iodine into the var...
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ژورنال
عنوان ژورنال: Thyroid Research
سال: 2011
ISSN: 1756-6614
DOI: 10.1186/1756-6614-4-10